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Publications

Discover peer-reviewed publications by therapeutic area.
The information on this page pertains to select publication resources. It is not intended to serve as a comprehensive list of all publications resources.
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Any content about investigational therapeutics or investigational uses of locally approved products does not establish the safety or efficacy of these therapeutics or uses, and there is no guarantee of local regulatory approval.
The provision of this content is not intended to recommend or suggest use of its products in any manner inconsistent with local regulatory approval. For questions beyond a product’s authorized indications or for information not available here, please contact Alnylam Medical Information.

Publications

Transthyretin Amyloidosis (ATTR)

Influence of Disease-Modifying Therapy on the Efficacy of Vutrisiran in Transthyretin Cardiac Amyloidosis

Journal of the American College of Cardiology

Author(s)

Arielle Abovich, Marianna Fontana, Brian Claggett, et al

Transthyretin Amyloidosis (ATTR)

Effect of Vutrisiran According to Baseline Tafamidis Use in Transthyretin Amyloidosis with Cardiomyopathy: Insights From HELIOS-B

Journal of the American College of Cardiology

Author(s)

Yasuhiro Hamatani, Brian L Claggett, Sarah AM Cuddy, et al

Transthyretin Amyloidosis (ATTR)

Vutrisiran Treatment and Changes in Cardiac Parameters and Amyloid Burden Assessed by Cardiovascular MRI

Journal of the American Medical Association

Author(s)

Yousuf Razvi, Awais Sheikh, Rishi K. Patel, et al

Transthyretin Amyloidosis (ATTR)

Comorbidity Burden in Transthyretin Amyloidosis With Cardiomyopathy: Insights From the HELIOS-B Trial

Journal of the American College of Cardiology

Author(s)

Sarah M. Birkhoelzer, Yasuhiro Hamatani, Karola S Jering, et al

Acute Hepatic Porphyria (AHP)

Givosiran treatment over 36 months for people with acute hepatic porphyria: a plain language summary

Future of Rare Disease

Author(s)

Kristen Wheeden, Sue Burrell, Susana Monroy, et al

Transthyretin Amyloidosis (ATTR)

Consistent Efficacy of Vutrisiran Across Sexes in Transthyretin Cardiac Amyloidosis: Evidence from the HELIOS-B Trial

European Journal of Heart Failure

Author(s)

Josephine Mansell, Xiaowen Wang, Karola S Jering, et al

Transthyretin Amyloidosis (ATTR)

Vutrisiran-Mediated Knockdown of Transthyretin in Patients with ATTR Amyloidosis

Clinical Pharmacokinetics

Author(s)

Marianna Fontana, Vincent Algalarrondo, Pablo Garcia-Pavia, et al

Transthyretin Amyloidosis (ATTR)

Vutrisiran in East Asian Patients With Transthyretin Amyloidosis With Cardiomyopathy: Post-Hoc Analysis of HELIOS-B

JACC: Asia

Author(s)

Jin Endo, Tetsuo Minamino, Jaewon Oh, et al