Therapeutic Areas

Acute Hepatic Porphyria (AHP)
Acute Hepatic Porphyria (AHP)
Transthyretin (ATTR) Amyloidosis
Transthyretin Amyloidosis (ATTR)
Primary Hyperoxaluria Type 1 (PH1)
Primary Hyperoxaluria Type 1 (PH1)
Neurologic
Neurologic
Cardiovascular (CV)
Cardiovascular (CV)

 Science of RNAi

RNAi Mechanism of Action RNAi Mechanism of Action

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Video

RNAi Mechanism of Action

This video highlights the mechanism of action (MOA) of RNAi therapeutics and its role in silencing gene expression. This video is intended to be viewed in its entirety.

View more on Alnylam & RNAi Science 

Congresses

Congress-AAN Upcoming

Transthyretin Amyloidosis (ATTR)

American Academy of Neurology (AAN) 2026

Congress-AHA-thumbnail
Congress-AHA-thumbnail

Transthyretin Amyloidosis (ATTR)

American College of Cardiology (ACC) 2026

Publications

Transthyretin Amyloidosis (ATTR)

Effect of vutrisiran on components of health status in transthyretin amyloidosis with cardiomyopathy: the HELIOS-B study

European Journal of Heart Failure

Author(s)

Yasuhiro Hamatani, Brian L Claggett, Muthiah Vaduganathan, et al

Transthyretin Amyloidosis (ATTR)

Efficacy and Safety of Vutrisiran in Patients with Hereditary Transthyretin-mediated Amyloidosis with Polyneuropathy: Analysis of the East Asian Subpopulation from HELIOS-A

Neurology and Therapy

Author(s)

Jeeyoung Oh, Yoshiki Sekijima, Hideki Mochizuki, et al

Primary Hyperoxaluria Type 1 (PH1)

Final Results of the ILLUMINATE-A Phase 3 Clinical Trial of Lumasiran for Primary Hyperoxaluria 1

Clinical Journal of the American Society of Nephrology

Author(s)

Yaacov Frishberg, Jeffrey M. Saland, John Lieske, et al

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Medical Information

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Adverse Events/Therapy Complaints

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Clinical Trials

Clinical Trials

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