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RNAiScience Data Hall

This website was created for healthcare professionals to provide access to educational and scientific information about Alnylam's RNAi platform and our data from congresses and publications.

Learn about RNAi

Therapeutic Areas

Acute Hepatic Porphyria (AHP)
Acute Hepatic Porphyria (AHP)
Transthyretin (ATTR) Amyloidosis
Transthyretin Amyloidosis (ATTR)
Primary Hyperoxaluria Type 1 (PH1)
Primary Hyperoxaluria Type 1 (PH1)
Neurologic
Neurologic
Cardiovascular (CV)
Cardiovascular (CV)

 Science of RNAi

RNAi Mechanism of Action RNAi Mechanism of Action

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Video Icon

Video

RNAi Mechanism of Action

This video highlights the mechanism of action (MOA) of RNAi therapeutics and its role in silencing gene expression. This video is intended to be viewed in its entirety.

View more on Alnylam & RNAi Science 

Congresses

Krakow_EHDN_Mobile Upcoming
Denver-Mobile Upcoming

Primary Hyperoxaluria Type 1 (PH1)

American Society of Nephrology (ASN) 2026

Phoenix-Mobile

Transthyretin Amyloidosis (ATTR)

Heart Failure Society of America (HFSA) 2026

Publications

Transthyretin Amyloidosis (ATTR)

Continuous Vutrisiran Reduces Cardiovascular Events and Hospitalizations in Patients With Transthyretin Amyloidosis With Cardiomyopathy in the HELIOS-B One-Year Open Label Extension

Journal of Cardiac Failure

Author(s)

Sarah A M Cuddy, Jan M Griffin, W H Wilson Tang, et al

Transthyretin Amyloidosis (ATTR)

Influence of Disease-Modifying Therapy on the Efficacy of Vutrisiran in Transthyretin Cardiac Amyloidosis

Journal of the American College of Cardiology

Author(s)

Arielle Abovich, Marianna Fontana, Brian Claggett, et al

Transthyretin Amyloidosis (ATTR)

Effect of Vutrisiran According to Baseline Tafamidis Use in Transthyretin Amyloidosis with Cardiomyopathy: Insights From HELIOS-B

Journal of the American College of Cardiology

Author(s)

Yasuhiro Hamatani, Brian L Claggett, Sarah AM Cuddy, et al

 Connect with Alnylam Medical

For further information or questions related to Alnylam's clinical data, connect with Alnylam Medical.

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Medical Information

Medical Information

For Medical Information inquiries, please submit your question using the email below.

For country-specific Medical Information contact details, please navigate to the individual country sites located at Alnylam.com.

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Adverse Events/Therapy Complaints

Adverse Events/Product Complaints

To report an adverse event or to submit a product complaint, please use the email below.

For country-specific contact details, please navigate to the individual country sites located at Alnylam.com.

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Clinical Trials

Clinical Trials

For clinical trial inquiries, please use the contact options below.